The protocol for evaluating the Join Us Move, Play (JUMP) program, a whole-systems strategy for boosting physical activity in children and young people (5-14 years) within Bradford, UK, is described in this paper using a citizen science approach.
The JUMP program evaluation seeks to grasp children's and families' firsthand accounts of physical activity and their involvement. Incorporating focus groups, parent-child dyad interviews, and participatory research, this study adopts a collaborative and contributory citizen science approach. Changes to both this study and the JUMP program will be informed by feedback and data analysis. Furthermore, we intend to explore the citizen science experience of participants, and the appropriateness of citizen science for evaluating a comprehensive systems strategy. The iterative analysis approach, combined with a framework, will be used to analyze the data gathered from the collaborative citizen science study, involving citizen scientists.
The University of Bradford has granted ethical approval to study one (E891 focus groups, a component of the control trial, and E982 parent-child dyad interviews) and study two (E992). Peer-reviewed journal publications will detail the results, alongside summaries distributed to participants through schools or individually. To amplify dissemination, citizen scientists' feedback will be incorporated.
Study one, which encompasses E891 focus groups (part of the control trial) and E982 parent-child dyad interviews, and study two (E992), have been approved ethically by the University of Bradford. Peer-reviewed journal publications will detail the outcomes, while summaries will be distributed to participants via schools or direct delivery. The dissemination of information will be enhanced by the contributions of citizen scientists.

To comprehensively review empirical evidence on the family's role in end-of-life communication and pinpoint the fundamental communication methods for end-of-life decision-making in family-centered cultural settings.
Communication parameters relating to the end of line protocol.
This integrative review's methodology was structured according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting principles. Papers on end-of-life communication with families, published from 1 January 1991 to 31 December 2021, were identified via a search of four databases—PsycINFO, Embase, MEDLINE, and the Ovid nursing database—utilizing the keywords 'end-of-life', 'communication', and 'family'. Following extraction, data were coded into themes to guide the subsequent analysis. A quality assessment was undertaken for all 53 eligible studies selected via the search strategy. Using the Quality Assessment Tool, quantitative studies were evaluated, and the Joanna Briggs Institute Critical Appraisal Checklist was applied to qualitative research.
Family-focused research on end-of-life communication: an evidence-based approach.
Analysis of these studies reveals four overarching themes: (1) disputes in families about end-of-life decision-making, (2) the crucial element of timing in end-of-life communication, (3) the difficulty in determining who should be the key decision-maker in end-of-life care, and (4) differing cultural perspectives on end-of-life communication.
The current review revealed the necessity of family in end-of-life communication, implying that family participation likely contributes to improvements in the patient's quality of life and experience of death. Future studies should aim to develop a family-sensitive communication framework, appropriate for Chinese and Eastern contexts, to address family expectations in the disclosure of a prognosis, support patients' fulfillment of family roles, and aid in the decision-making process for end-of-life issues. To provide comprehensive end-of-life care, clinicians must acknowledge the impact of family and strategically manage family member expectations, considering their unique cultural contexts.
The review of current literature highlighted the significance of family in end-of-life discussions, implying that family engagement is likely to contribute to a better patient experience during their final stages. Further investigation necessitates the development of a family-centric communication framework tailored to Chinese and Eastern cultural contexts, aiming to manage familial expectations during prognosis disclosure, support patients' fulfillment of familial responsibilities, and guide end-of-life decision-making. GSK2245840 Clinicians should recognize the critical role families play in end-of-life care and adapt their management of family member expectations to diverse cultural contexts.

To understand patients' experiences with the enhanced recovery after surgery (ERAS) pathway and identify impediments to the implementation of ERAS from a patient's standpoint is the purpose of this research.
The Joanna Briggs Institute's methodology for synthesis guided the systematic review and qualitative analysis.
A systematic search for relevant studies, published within four databases—Web of Science, PubMed, Ovid Embase, and the Cochrane Library—was performed, augmented by the input from key authors and the review of their reference materials.
Within the scope of the ERAS program, 31 studies encompassed 1069 surgical patients. To identify relevant articles, inclusion and exclusion criteria were formulated according to the Population, Interest, Context, and Study Design standards established by the Joanna Briggs Institute. The study's inclusion criteria involved ERAS patient narratives, qualitative data expressed in English, and publications originating between January 1990 and August 2021.
The Qualitative Assessment and Review Instrument from the Joanna Briggs Institute, a standardized data extraction tool, was used to collect data from the relevant studies focused on qualitative research.
The structural framework of patient experience centers on the importance of prompt healthcare responses, the professionalism of family-centered care, and the misunderstanding and anxiety around the ERAS program's safety. Regarding the process dimension, patients highlighted the following themes: (1) the need for accurate and sufficient information from healthcare professionals; (2) the necessity for effective communication between patients and healthcare professionals; (3) the desire for tailored treatment plans; and (4) the importance of ongoing follow-up support. Short-term bioassays The outcome dimension revealed a shared patient desire to effectively resolve severe postoperative symptoms.
By gauging ERAS from the viewpoint of the patient, weaknesses in clinical care are made evident, and this identification allows for swift solutions to patient recovery issues, thereby mitigating impediments to the introduction of ERAS.
The item CRD42021278631 should be returned immediately.
CRD42021278631: The following item, CRD42021278631, is included.

A concerning consequence of severe mental illness is the risk of premature frailty. A crucial, unmet requirement exists for an intervention that mitigates the risk of frailty and lessens the detrimental consequences it brings to this population. The objective of this study is to supply novel data on the practicability, acceptance, and initial efficacy of Comprehensive Geriatric Assessment (CGA) in improving health results for people who have both frailty and severe mental illness.
Metro South Addiction and Mental Health Service outpatient clinics will serve as the recruitment point for twenty-five participants, showing frailty and severe mental illness, between the ages of 18 and 64, who will be given the CGA. Primary outcome measures will determine the degree to which the embedded CGA is both feasible and acceptable within the context of routine healthcare. Variables of significant interest are frailty status, quality of life, polypharmacy, and the broader context of mental and physical well-being.
The Metro South Human Research Ethics Committee (HREC/2022/QMS/82272) sanctioned all human subject/patient procedures. Peer-reviewed publications and conference presentations will serve as channels for disseminating the study's findings.
Metro South Human Research Ethics Committee (HREC/2022/QMS/82272) approved all procedures involving human subjects/patients. The dissemination of study findings will occur through the channels of peer-reviewed publications and conference presentations.

This study sought to develop and validate nomograms that accurately predict patient survival in the context of breast invasive micropapillary carcinoma (IMPC), which is essential for informed objective decision-making in patient care.
Nomograms were developed using Cox proportional hazards regression analysis to predict 3- and 5-year overall survival and breast cancer-specific survival, based on identified prognostic factors. Clinical biomarker Kaplan-Meier analysis, calibration curves, the area under the curve (AUC), and the C-index (concordance index) were utilized to gauge the effectiveness of the nomograms. Nomograms were benchmarked against the American Joint Committee on Cancer (AJCC) staging system, utilizing decision curve analysis (DCA), integrated discrimination improvement (IDI), and net reclassification improvement (NRI) as comparative tools.
Patient data were extracted from the Surveillance, Epidemiology, and End Results (SEER) database system. Eighteen U.S. population-based cancer registries contribute cancer incidence data to this database.
We excluded 1893 patients from our analysis, and subsequently included 1340 for the current study.
The AJCC8 stage's C-index (0.670) was lower than the OS nomogram's C-index (0.766). Critically, the OS nomograms demonstrated superior AUC performance compared to the AJCC8 stage (3 years: 0.839 vs 0.735; 5 years: 0.787 vs 0.658). Calibration plots demonstrated a good match between predicted and actual outcomes, with DCA revealing that nomograms showcased enhanced clinical utility in comparison to the conventional prognostic tool.